This group is interested in the development of novel green synthetic methodologies, utilizing transition metal catalysis, for the functionalization of aromatic hydrocarbons. Our newly developed catalytic reactions provide rapid access to previously inaccessible materials which can have potential applications in wide range of areas inc...
Labs
The focus of the Translational Bioinformatics group broadly focuses on developing and utilizing computational and statistical techniques for the analysis and visualization of transcriptomic data generated by high-throughput genomic technologies. This is an emerging area advancing in the facilitation of better understanding of traditio...
Biomedical Informatics Research Laboratory (BIRL) at LUMS aims to develop next generation modelling and simulation software for applications in proteomics and Systems Biology. Currently, the lab is developing a next-generation multiscale cancer modelling and simulation pipeline for integrative investigations into tumorigenesis. The gr...
Afzal lab emphasis on understanding the role of the multifunctional protein RIN4, which regulates both branches of the plant immune system. Plants employ multiple layers of immunity to guard against infection. The first layer responds to structures within conserved microbial molecules. The second layer responds to effector proteins, w...
The laboratory is dedicated to understanding the association of diabetes with respiratory tract infections caused by Streptococcus pneumoniae, which is a cause of at least 40% of total pneumonia infections and invasive pneumococcal disease. The research program is comprised of four major components which are as follows; i) Investigati...
Epigenetics group is interested in understanding how cell fates are established and how they are maintained during development. In particular, Tariq lab works on Polycomb (PcG) and Trithorax group (TrxG) genes which are involved in maintaining epigenetic states of gene expression. Molecular and biochemical approaches are being used in...
The focus of the Computational Genomics and Systems Biology group is to develop and apply computational and mathematical methods in the area of modern biology to understand how biological systems function and evolve over time. Specifically, such approaches are being employed to decipher the genetics of bread wheat and understand the t...
Cancer Therapeutics group focuses on identifying and characterizing novel synthetic and natural compounds with therapeutic potential for cancer. This involves assay-guided isolation and synthesis of compounds with anti-proliferative activities against cancer cell lines of different origins and identifying their mechanism of action. We...
Currently, Hussan lab focuses on the following areas: 1- Understanding the structural and conformational properties of antibody target sites on the envelope glycoproteins of hepatitis C virus (HCV) by using NMR techniques to obtain necessary information required for structure based vaccine design. 2- Discovery of new HCV neutralizing...